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In Act III, Scene 5, Hecate is a fourth witch, introduced in this scene; she is angered that she has not been consulted by the three sisters as they have "traded and trafficked" with Macbeth. Furthermore, the three witches have made mistakes. She tells them,
And, which is worse, all you have done
Hath been but for a wayward son,
Spiteful and wrathful: who, as others do,
Loves for his own ends, not for you. (3.5.10-13)
"Wayward son" is a metaphor for Macbeth, who has been resistant to the witches' guidance and influence.
So, Hecate tells the other witches that she will conjure "a dismal and a fatal end" for Macbeth. The fate that she will mix up for Macbeth, Hecate declares, will cause him to become overly confident, and
He shall spurn fate, scorn death, and bear
His hopes ’bove wisdom, grace, and fear.
And you all know security
Is mortals’ chiefest enemy. (3.5.30-33)
In this passage, "fate," "death," and "security," "wisdom," "grace," and "fear" are all personified as they are given the qualities of animate beings which can be the recipients of emotion.
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