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The best way to respond to this section might be to observe that genetic factors are very important in interacting with environmental factors when it comes to developing depression. The study shows that some people, i.e. those with certain genotypes, were more likely to develop adulthood depression symptoms after a series of negative childhood experiences. In some other cases, genotypes could actually mediate to make children who experienced negative environments growing up less likely to suffer from depression later in life. This includes certain environments more likely to contribute to depression, like growing up in a rural setting, a strong predictor for future depression. So the reaction would have to be that both nature and nurture play a major role in depression, but neither on their own.
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