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Please explain this quote from Frankenstein: Death is not the greatest loss in life....

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Please explain this quote from Frankenstein: Death is not the greatest loss in life. The greatest loss is what dies inside us while we live.

I do not understand how to apply this quote with reference to Frankenstein

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First, are you sure that this quotation comes from Frankenstein?

I ask because a number of references attribute it to Norman Cousins, a writer and peace activist who battled serious illness for some time. In the context of Cousins' life, it referred to the need to keep the human spirit alive in the face of pain and fear--staying spiritually alive in the face of death.

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