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One of the postulates of collision theory of reactions is that the reacting species approach at the correct attitude. e.g for the reaction between monobromomethane (methyl bromide) and sodium hydroxide to make methanol the hydroxide ion has to approach the methyl bromide molecule from the side opposite the bromine atom for best chance of reaction occurring.
- If the reactant does not have enough energy
-If the colliding molecules aren't oriented correctly
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