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The best analogy for a lysosome and a house with mice is a mousetrap. In particular, one of those larger mousetraps that is a completely enclosed space with a small opening where a mouse can be lured in but cannot get out. A lysosome is a vesicle within a cell that holds waste or other unwanted materials until they can be ejected from the cell. The mousetrap holds the unwanted mouse until a person can come along and dispose of the mouse outside of the house. This is the best analogy I can think of.
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