8q34.8 refers to a genetic locus. Explain the meaning of this series of numbers and letters.



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Posted on (Answer #1)

The first number represents the chromosome number. The given gene is therefore in Chromosome 8 (8q34.8).

The letter following the chromosome number indicates major location. There are two possibilities - p and q. p refers to the short arm, while q the long arm. The given gene is therefore located in the long arm of Chromosome 8 (8q34.8). 

The last three numbers give the region, band and sub-band. The given locus, for instance, is located in region 3, band 4, sub-band 8 of the long arm of Chromosome 8.


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