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Has the flu ever reached epidemic proportions?

Three times in the twentieth century, influenza caused by a contagious virus reached epidemic (widespread outbreaks) proportions worldwide. In 1918 and 1919, 30,000,000 people died during a two-wave global flu epidemic, 500,000 of them Americans. After the flu weakened their immune systems, many sufferers caught other illnesses, such as pneumonia, which proved to be fatal. After antibiotics (substances that kill bacteria, that is, germs) such as sulfa and penicillin were developed and went on the market in the mid-1940s, fewer people died from secondary infections that were caused by bacteria. Even so, viruses cause flu and antibiotics kill only bacteria, not viruses. Therefore, when the Asian flu erupted in global proportions in 1957 and 1958, it killed 70,000 Americans (figures for the rest of the world are unknown), and when the Hong Kong flu broke out in 1968...

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1. Origins
   1. How did early humans cure illness and disease?
   2. Who was the first doctor in history?
   3. What is the Hippocratic Oath?
   4. What are the four humors?
   5. When did biological warfare originate?
   6. Were there hospitals before the Middle Ages?
   7. When was the first North American hospital built?
   8. What advances were made in medicine during the Renaissance?
   9. How old is the concept of public health?
   10. What is Gray's Anatomy?
2. Modern Medicine
   1. When did modern medicine begin?
   2. Who invented vaccination?
   3. When did modern surgery begin?
   4. When was anesthesia first used?
   5. What surgical advances were introduced in the late twentieth century?
   6. Who introduced the use of antiseptics in hospitals?
   7. What are Louis Pasteur's contributions to the study of disease?
   8. When were antibiotics invented?
   9. Why are new antibiotics constantly being developed?
   10. Why is Florence Nightingale famous?
   11. When was the International Red Cross founded?
   12. Who discovered the X ray?
   13. Who was Clara Barton?
   14. What were the Curies' contributions to medicine?
   15. How did Jonas Salk and Albert B. Sabin save lives?
   16. When did the first heart transplant take place?
   17. When was the first test-tube baby born?
   18. When was the first kidney transplant?
   19. What is leprosy?
   20. What is the plague?
   21. Is yellow fever still a deadly disease?
   22. What was the first disease conquered by humans?
   23. Do scientists know when the AIDS virus first appeared?
   24. Who was Typhoid Mary?
   25. Has the flu ever reached epidemic proportions?
   26. What are CT and MRI scans?
3. Psychology
   1. Why are Pavlov's dogs famous?
   2. What is behaviorism?
   3. What were Sigmund Freud's contributions to the study of human psychology?
   4. What does the term "Jungian" mean?
   5. Who was Dorothea Dix
   6. What is depression?

1. Middle Ages