Weissenbacher-Zweymuller syndrome
Definition
Weissenbacher-Zweymuller syndrome (WZS) is a genetic form of dwarfism in which affected individuals are born with small, underdeveloped jaws (micrognathia), cleft palate, short arms and legs (rhizomelia), "dumbbell" shaped arm and leg bones, protruding wide spaced eyes (hypertelorism), and incompletely formed back bones (vertebral coronal clefts). Unlike most other forms of dwarfism, individuals affected by Weissebacher-Zweymuller start out being affected by dwarfism, and then have a period of gradual growth and bone change that leads to normal physical development by age 5–6 years.
Description
Weissenbacher-Zweymuller syndrome refers to a rare disorder of small underdeveloped jaws (micrognathia), delayed bone growth, and unusual bone formation first described in 1964 by...
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