Spinal muscular atrophy

Definition

Spinal muscular atrophy (SMA) is a disease characterized by degradation of the anterior horn cells of the spinal cord and has similar characteristics to Spinobulbar muscular atrophy (SBMA). SBMA differs from SMA in its mode of inheritance, the disease-determining gene, the mutational events that trigger disease and the cellular specificity of the disease pathology.

Description

The anterior horn cells control the voluntary muscle contractions from large muscle groups such as the arms and legs. For example, if an individual wants to move his/her arm, electrical impulses are sent from the brain down the anterior horn cells to the muscles...

[The entire page is 2059 words long]

Join eNotes

The above is a free excerpt. Get total access to this content with the: