Neurofibromatosis

Definition

Neurofibromatosis (NF), or von Recklinghausen disease, is a disorder which causes development of multiple soft tumors (neurofibromas). These tumors occur under the skin and throughout the nervous system (cells which control body movement and sensation).

Description

Neural crest cells are primitive cells which exist during fetal development. These cells eventually turn into cells that form nerves throughout the brain, spinal cord, and body. Collectively, this system of nerve cells is called the nervous system, which coordinates movement and sensation. Some nerve cells carry impulses from the brain to muscles or other peripheral structures, hence the name peripheral nervous system. Another group of nerve cells called the central nervous system are capable of transmitting sensation back...

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