Home > Encyclopedia of Genetic Disorders > Multiple lentigenes syndrome

Definition

Multiple lentigenes syndrome is a rare genetic condition that causes the affected individual to have many dark brown or black freckle-like spots on the skin, as well as other symptoms.

Description

Multiple lentigenes syndrome is a genetic disorder that results in characteristic marking of the skin, abnormalities in the structure and function of the heart, hearing loss, wide-set eyes, and other symptoms. Other terms for multiple lentigenes syndrome include cardiomyopathic lentiginosis and LEOPARD syndrome. LEOPARD syndrome is an acronym for the seven most commonly observed symptoms of the disorder:

• (L)entigenes, or small dark brown and black spots on the skin;
• (E)lectrocardiographic conduction defects, or abnormalities of the muscle activity in the heart;
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