Muir-Torre syndrome

Definition

A syndrome is a condition in which a certain set of features is regularly seen. In Muir-Torre syndrome, the consistent features are skin tumors (sebaceous neoplasms) and internal organ cancers, most commonly colon cancer.

Description

Muir-Torre syndrome is named for two authors who provided some of the earliest descriptions of the condition, Muir in 1967 and Torre in 1968. Originally thought to be separate conditions, it is now known that Muir-Torre syndrome and Hereditary non-polyposis colon cancer (HNPCC), also known as Lynch syndrome, are due to alterations in the same genes. Some of the features of the conditions are the same including increased risk of colorectal cancer (cancer of the colon and rectum) and cancer of other organs. Both conditions are hereditary cancer...

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