Lebers hereditary optic atrophy
Definition
Lebers hereditary optic atrophy is a painless loss of central vision (blurring of objects and colors appearing less vivid) that usually begins between the ages of 25 and 35 (but can occur at any age) and leads to legal blindness. Other minor problems may be present such as tremors, numbness or weakness in arms and legs, or loss of ankle reflexes. It was first described in 1871 by Theodore Leber and is the most common cause of optic atrophy.
Description
Lebers hereditary optic atrophy is also called Lebers hereditary optic neuropathy or LHON. The beginning of visual blurring in both eyes is called the acute phase of LHON. In about half the patients, both eyes are affected at the same time. In the remainder of patients, central vision is lost in one eye over a period of a few weeks,...
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