Home > Encyclopedia of Genetic Disorders > Kartagener syndrome

Definition

Kartagener (pronounced KART-agayner) syndrome refers to a condition that involves difficulty with clearing mucus secretions from the respiratory tract, male infertility, and situs inversus. The defining characteristic of this syndrome is the situs inversus, which is a reversal of abdominal and thoracic organs.

Description

This syndrome is named after Kartagener, a physician from Switzerland. In the 1930's, Kartagener and a colleague described a familial form of bronchiectasis with situs inversus and nasal polyps. This came to be known as Kartagener syndrome. Kartagener syndrome is also known as the Siewert syndrome, after another physician, Siewert, who described the syndrome in the early 1900's.

Individuals who have Kartagener syndrome form a subset of the disorder called...