Greig cephalopolysyndactyly
Definition
Greig cephalopolysyndactyly is a very rare autosomal dominant disorder. The syndrome is characterized by physical abnormalities of the head, face, fingers and toes. Distinct features include extra fingers and/or toes; a large and unusual shape of the skull; a high, prominent forehead; and widely spaced eyes. The range and severity of symptoms may vary greatly between individuals. Some individuals with Greig cephalopolysyndactyly require medical or surgical intervention to manage these problems. The syndrome is familial and in most cases is transmitted as an autosomal dominant trait.
Description
The disorder is named for D. M. Greig (pronounced Gregg), a Scottish physician, who first described the features of this syndrome in 1926. He saw a mother and her daughter who had a...
[The entire page is 1926 words long]
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