Dec 21, 2009

Encyclopedia of Genetic Disorders | Dysplasia

Definition

Dysplasia is a combination of two Greek words; dys-, which means difficult or disordered; and plassein, to form. In other words, dysplasia is the abnormal or disordered organization of cells into tissues. All abnormalities relating to abnormal tissue formation are classified as dysplasias.

Description

Tissues displaying abnormal cellular organization are called dysplastic. Dysplasias may occur as the result of any number of stimuli. Additionally dysplasia may occur as a localized or a generalized abnormality. In a localized dysplasia, the tissue abnormality is confined to the tissue in a single area, or body part. In a generalized dysplasia, the abnormal tissue is an original defect leading to structural consequences in different body parts.

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