Home > Encyclopedia of Genetic Disorders > Craniosynostosis

Definition

Craniosynostosis is a congenital abnormality of the central nervous system that involves the premature closing of one or more of the fibrous joints between the bones of the skull (cranial sutures).

Description

Craniosynostosis is a birth defect that affects the shape of the skull. Individuals born with craniosynostosis have abnormally shaped heads and a prominent bony ridge over the affected suture or sutures. All affected individuals also are likely to experience water on the brain (hydrocephalus) that can cause enlargement of the head and increased pressure inside the skull. Developmental delay is commonly experienced by those individuals affected by craniosynostosis.

There are two major...