Ephedra - Reactions with Other Drugs or Substances

Reactions with Other Drugs or Substances

Ephedra supplements typically contain caffeine. Users may already be consuming caffeine in carbonated beverages, coffee, or tea. Mixing caffeine with ephedrine increases the stimulant effects on the heart, making the user more anxious and edgy. "Ephedrine/caffeine/aspirin combinations are often 'stacked' by weight lifters, and used for weight loss," noted Kuhn prior to the substance's ban. Ephedra is especially dangerous when used in combination with over-the-counter or prescription decongestants, any other stimulants, and certain drugs used to treat depression.