Dextroamphetamine - Overview

Overview

Dextroamphetamines are addictive drugs that have a high rate of abuse. The prefix "dextro" in the drug name dextroamphetamine refers to dextrose, a type of sugar. Dextroamphetamines are simply amphetamines that contain sugar molecules. (An entry on amphetamines is also available in this encyclopedia.)

The history of amphetamines stretches back to the late nineteenth century. The drug was first synthesized, or made in a laboratory, in 1887. However, it was not used until 1932 when the drug manufacturer Smith, Kline and French introduced Benzedrine. Packaged as an over-the-counter inhaler, the amphetamine drug Benzedrine helped relieve nasal congestion.

Dextroamphetamine: The Drug with Multiple Uses

Throughout the 1930s, doctors in Europe prescribed amphetamines to treat colds, hay fever, and asthma. That same decade, amphetamines became available in tablet form for the treatment of the daytime sleeping disorder known as narcolepsyA sleep disorder characterized by daytime tiredness and sudden attacks of sleep., a fairly rare condition that causes people to fall asleep quickly and unexpectedly. Later, many Americans became hooked on amphetamines—specifically the dextroamphetamine sulfate Dexedrine—after finding that users could lose weight quickly and effortlessly. Only then did researchers begin to realize that these drugs could be dangerous and addictive.

One of dextroamphetamines street names is copilot. The drug is still routinely used by Air Force pilots on long missions to help keep them awake and alert.  Aero Graphics, Inc./Corbis.
One of dextroamphetamine's street names is "copilot." The drug is still routinely used by Air Force pilots on long missions to help keep them awake and alert. © Aero Graphics, Inc./Corbis.

During World War II (1939–1945), amphetamines were distributed among soldiers from the United States, the United Kingdom, Germany, and Japan to keep them awake and alert on the battlefield. Back on the home front, people who worked in factories manufacturing goods for the war effort were also using the drug to boost their productivity. After the war, use of the drug continued, both in the United States and abroad.

Access to Amphetamines Is Restricted

Amphetamines and dextroamphetamines became the drug of choice for people who needed a lift or who needed to stay alert. Night-shift workers, students cramming for exams, and truck drivers on long hauls were among the most common users. The addictive nature of the drugs contributed to the growing demand for them. In 1970, drug companies in the United States produced about 12 million amphetamine tablets. A large percentage of these drugs fell into the wrong hands and made their way to the black marketThe illegal sale or trade of goods; drug dealers are said to carry out their business on the black market.. That year, the U.S. Congress passed the Controlled Substances Act (CSA) in an effort to stop the huge increase in drug use. The new law restricted the use of amphetamines and classified them as Schedule II drugs—drugs with genuine medical uses that nevertheless possess a high potential for abuse and dependency.