Benzylpiperazine/Trifluoromethylphenylpiperazine - Reactions with Other Drugs or Substances
Reactions with Other Drugs or Substances
The DEA reports that BZP and TFMPP are sometimes deliberately mixed with ecstasy by drug dealers and then sold as ecstasy. Some users hoping for an extended or intensified high from ecstasy will knowingly combine these drugs. A DEA "Drug Intelligence Brief" described the drug-related death of a 23-year-old woman in Zurich, Switzerland, after she had consumed both BZP and ecstasy. Medical evidence suggests that the drug combination made her extremely thirsty. Before going into a coma, she consumed 10 liters of water in just 15 hours. The young woman experienced high blood pressure and brain swelling prior to her death.
Users have reported combining BZP with alcohol, Xanax (a benzodiazepine), dextromethorphan, marijuana, and hydrocodone (a steroid). They have described many of their experiences as frightening or unpleasant. A New Zealand alcohol and drug service expert was quoted in the Ashburton Guardian as saying that the "herbal highs" associated with BZP use are intensified by alcohol.
Warnings are given against combining prescription piperazines, used to treat parasitic infections, with certain psychiatric medications. The combination may cause violent seizures or convulsions. Piperazines are especially dangerous when used by people with kidney disease, liver disease, or a history of epilepsy.
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