von Recklinghausen's Neurofibromatosis
Definition
Von Recklinghausen's neurofibromatosis is also called von Recklinghausen disease or simply neurofibromatosis (NF). It is an automsomal dominant hereditary disorder. NF is the most common neurological disorder caused by a single gene. Patients develop multiple soft tumors (neurofibromas) and very often skin spots (freckling AND café au lait). The tumors occur under the skin and throughout the nervous system.
Description
There are three types of neurofibromatosis. The two main types of neurofibromatosis are Neurofibromatosis 1 (NF1) and Neurofibromatosis 2 (NF2). NF1 is more common than NF2. NF1 affects approximately 1 in 2, 000 to 1 in 5, 000 births worldwide. NF2 affects 1 in 35, 000 to 1 in...
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