Suramin

Definition

Suramin (suramin hexasodium; CI-1003) is a polysulfonated naphthylurea. It is a growth factor antagonist for palliative treatment in hormone-refractory prostate cancer and hormone-responsive metastatic prostate cancer.

Purpose

Suramin has been used for years to combat African sleeping sickness and river blindness but it has also been found beneficial in slowing the progression of prostate cancer. This drug is classified as an antiprotozoal or anthelminitic. In addition to combating prostate cancer, suramin has demonstrated anti-tumor activity against many types of tumors including endometrial, breast, ovarian, and lung cancer. It has a number of important biological functions for cancer...

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