Sirolimus

Definition

Sirolimus is indicated by the Food and Drug Administration (FDA) to be used after a kidney transplant to prevent the body from rejecting the new kidney. Sirolimus may also have a role in prevention of organ rejection in heart or lung transplantation, and prevention of graft-versus-host disease in patients undergoing bone marrow transplantation. Sirolimus (formerly known as rapamycin) became available at the end of 1999 and is marketed under the brand name Rapamune by Wyeth-Ayerst Laboratories.

Description

Sirolimus belongs to a class of macrolide antibiotics and is isolated from an organism named streptomyces...

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