Demeclocycline

Definition

Demeclocycline, more accurately demeclocycline hydrochloride, is a broad-spectrum antibiotic of the tetracycline family. Demeclocycline is marketed under the trade name Declomycin.

Purpose

Demeclocycline is used to treat cancer patients who have developed a condition known as syndrome of inappropriate antidiuretic hormone (SIADH). A wide variety of malignacies, especially small-cell lung cancer, as well as various other non-cancer conditions, give rise to SIADH, which is caused by overproduction of antidiuretic hormone (ADH). SIADH can also develop as a side effect of the anticancer drugs

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