Buserelin

Definition

Buserelin is a synthetic analog of natural gonadotropin-releasing hormone and is used to treat prostate cancer. Buserelin, also called buserelin acetate, is sold under the brand name Suprefact in Canada. It is not commercially available in the U.S. for human use.

Purpose

Androgens, particularly testosterone, appear to play a major role in prostate cancer. Buserelin inhibits production of luteinizing hormone from the pituitary gland which decreases the levels of testosterone. Prostate cancer is often sensitive to testosterone levels, thus, a reduction in testosterone may influence the rate of cancer growth progression and...

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