Amsacrine
Definition
Amsacrine is an antitumor agent used to treat adult acute leukemia. It is no longer commercially available in the United States, although it is available in Canada.
Purpose
Amsacrine is an investigational drug used to treat refractory acute lymphocytic and nonlymphocytic leukemias, Hodgkin's disease, and non-Hodgkin's lymphomas. It may also have some activity against head and neck cancers.
Description
Amsacrine inhibits the synthesis of DNA. It also inhibits the enzyme responsible for cutting the strands of DNA, and untwists...
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